hello Team

can any one help me with flashing my Q Brain 25 amp ESC. 

Why do you want to flash them? I think they are already optimized for quads with better refresh rates.
Anyways cant find much info about flashing online, looks like it has never been done yet or done but no info shared.

Found some info that may help
http://diydrones.com/profiles/blogs/q-brain-4-x-20a-brushless-quadcopter-esc
http://www.rcgroups.com/forums/showthread.php?t=1953736

Why do you want to flash it ?    It's firmware is already optimised for multi rotors .